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[–] 2 pts

It could be caused by IVF. A lot can go wrong. Damage to the eggs, exposure to chemicals, damage during reentry, not getting a soul from the mother during zygote stage.

[–] 0 pt

That was my thought. If that donor had donated samples at a dozen different banks in half a dozen states that would imply correlation strongly, but if all the donation went through the same process in the same place then it's just as likely a local phenomenon.

[–] 1 pt

What's the average age of a woman seeking sperm donation?

Probably over 35, that's when the likelihood of birthing a child with mental defects and just about any other type of defect increases.