I had a friend with this. I can see how annoying it must be. My dad has it since he has gotten older. He cant hold a glass anymore. Have you tried beta blockers or gabapetin or botulinum? If you haven’t already you can check out clinicaltrials.gov for novel therapies.
Pretty much every single (Prescribed) drug besides benzos, Aderall or opiates or something is just complete shit and barely does anything. I don’t know the reason why this disease makes you shake but wouldn’t some benzo work? I know they give you that shit for alcohol withdrawal and DTs but I’m guessing the reason for the shaking is inherently different?
The disease is somehow related to the GABA neurtranmitter function. Which is basically how benzos work. Exclusively in GABA A I think.
Yup. It is. The reason you shake when withdrawing off alcohol is because when you’re drunk for so long that your body literally thinks it is now necessary for survival (it essentially is at that point) the level of gaba neurotransmitters is so filled at equilibrium that when you go cold turkey you start having DTs and could actually die. At rehab centers they put you on benzos for a good week and ween you off because it’s so dangerous when you are withdrawing from years of constant alcohol abuse. Benzos and alcohol are the only two drugs in existence that you can literally fucking die from if you stop immediately. If the disease works on gaba than alcohol benzos should work for sure.
gabapentin makes people insane
Well Ive never taken it but clearly there are some people that tolerate it well. Drugs have different effects on different people. Everything has trade offs. He may decide gabapentin is worth it for him.
I have never taken it myself but I have had several friends who were prescribed it and it changed their entire personality within days of starting the prescription. They went from friendly decent people to total assholes that I preferred not to be near practically overnight. I know it's just anecdotal but I have seen the transformation happen to at least ten people. It get progressively worse the longer they were taking the crap. I talked most of them into stopping ingesting that shit and their personality returned to what it used to be in a week or so. The people who did not stop taking it I no longer associate with because they are insufferable and I surely do not want to deal with that nonsense.
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