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Pay attention to your gut health if you don't have a great diet. https://www.sciencemag.org/news/2018/09/your-gut-directly-connected-your-brain-newly-discovered-neuron-circuit Edit: https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-021-01012-1

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"genetic predisposition"?

Diabetes, even in humans, is at its root, a genetic predisposition, per subject.

I see your quibble point though.... you seem to want to naysay all studies until they involve humans in front of you.

Of course to save money and time, many animal studies speed it up with animals designed to more readily be afflicted with disease being studied. You can buy a wide range of lab animals prone to certain conditions, with cancer animals being a major one.

In time, the papers citing diabetes surgery on aged rhesus macaques will appear, I predict, the gold standard animal, and large enough for precision surgeries.

Instead of forcing a selectively bred rhesus macaque pron to diabetes, it seems 9 out of 12 OBESE age 10 rhesus monkeys were naturally diabetic in one study, and raised in private cages. With a number as high as 9 in 12 seniors tilting to diabetes, it seems the darling animal of science, can be cheaply obtained by buying the supply of preexisting fat old monkeys, rather than waiting 10 years to appease you and your doubting.

I say that because you seem to be "species triggered" at the mice used in my first link. Natural occurring diabetes is high in old fat rhesus macaques, and provides ample test subjects to avoid a human trial to appease you. A human trial would also have to let the patient know that its only a 6 month cure anyways.

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They used this RIP-LCMV-GP mouse, which they call a diabetes model. I assume its been engineered for type 1 predisposition. The point is type 1 and type 2 have different pathologies. I would think you might have more luck fucking around with the stomach or small intestines based on the results seen in gastric surgery. It would be nice to accomplish the same results without cutting out peoples stomachs.

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natural standard version rhesus are over 50% diabetic if old and fat monkeys : 9/12 chance :

Chronic Treatment With a Melanocortin-4 Receptor Agonist Causes Weight Loss, Reduces Insulin Resistance, and Improves Cardiovascular Function in Diet-Induced Obese Rhesus Macaques

DOI: 10.2337/db12-0598

I would bet anything, a scalpel , or botox, would cure those old fat genetically predisposed monkeys, just like the mice.

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Melanocortin-4 Receptor Agonist Causes Weight Loss

Doctor:

the good news is we can cure your diabetes the bad news is you have to be black