Both mRNA and viral vector vaccines use RNA to create spike proteins. mRNA vaccines deliver the RNA into the cells with a lipid nanoparticle package. Viral vector vaccines produce the RNA inside the cells instead. For this, an adenovirus enters the cell and injects DNA into the nucleus. There, the DNA is used as a master to create the mRNA copies. The mRNA leaves the nucleus and functions like the mRNA from the mRNA vaccines.
Adenoviruses inject their DNA into the nucleus to create mRNA that acts as a blueprint for new adenoviruses. The manufacturers of the viral vector vaccines promise that this replication mechanism is disabled ("genetically changed so that it is impossible for it to grow in humans").
Both mRNA and viral vector vaccines use RNA to create spike proteins. mRNA vaccines deliver the RNA into the cells with a lipid nanoparticle package. Viral vector vaccines produce the RNA inside the cells instead. For this, an adenovirus enters the cell and injects DNA into the nucleus. There, the DNA is used as a master to create the mRNA copies. The mRNA leaves the nucleus and functions like the mRNA from the mRNA vaccines.
Adenoviruses inject their DNA into the nucleus to create mRNA that acts as a blueprint for new adenoviruses. The manufacturers of the viral vector vaccines promise that this replication mechanism is disabled ("genetically changed so that it is impossible for it to grow in humans").
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