>Twenty years ago, professor Fredrik Almqvist, an organic chemistry professor at Umeå University in Sweden, was asked by his collaborating researchers at Washington University in St. Louis (WashU) to design a compound that would prevent urinary tract infections, which are often caused by Gram-negative bacterial infections. >Almqvist’s team created various compounds that were then screened for their effects. >Rather than controlling Gram-negative bacteria adherence, they found some of the compounds were highly effective at killing various Gram-positive bacteria. These included multidrug-resistant strains classified as concerning threats by the U.S. Centers for Disease Control and Prevention (CDC). >The researchers singled out one compound, which they named PS757. Lab testing has shown PS757 to be effective against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecalis (VRE), multidrug-resistant Streptococcus pneumoniae, and erythromycin-resistant Streptococcus pyogenes (S. pyogenes), among others. >They further studied the effect of PS757 on S. pyogenes, a potentially flesh-eating bacteria, in animals. . . [Archive](https://archive.today/kbDjI)