>If the sequencers (Illumina, etc) use the Wuhan reference genome, then they are being very trustworthy of China. A digital mock up could be orchestrated to favor common "attachment" reads (where only the first several nucleotides are read) to statistically increase the chance of false positives. I don’t know the nitty gritty details of this shit. It seems like fucking insane that no one, no Russians, no Indians, no Muzzies or some rogue european researcher would try to verify the genome on his own. I cant find it now but there was some doc that showed all the sequences that the various major pcr assays were relying on. I believe the CDC had recommendations for which regions to test based on where the most diversity exists among betacoronaviruses— I think it was the N-protein. I think most of the pcrs are now using that section as one of the sequences. They certainly were not all using the spike and the orf1. I dont think any of them are using the spike protein. >The finer points of how the sequencers work make it hard for the layman to understand but a few youtube videos on how to use the machines and software should help clear some of it up. Yay I can’t wait. This is not my area and an I find it tedious to try to grasp a bunch of shit when I don’t have a lot of foundational knowlege to work from. But Im getting tired of hearing this same fucking disinformation story and not having the heavy artillery to knock it down. I get what you are saying though about reliance on software that infers a lot of data. I just don’t know how likely it would be for everyone to be relying on unconfirmed shit for a year and a half without trying to replicate the results. Well you certainly seem to have done your homework eh?