A new nanoparticle treatment is showing promise for glioblastoma, one of the most aggressive forms of brain cancer
A new plant-based nanoparticle treatment for glioblastoma, the fastest growing and most aggressive form of brain cancer, has been developed by scientists in China and the US.
Researchers from Renmin Hospital of Wuhan University and Yale University found that bardoxolone methyl (BM) – a phytochemical capable of self-assembly into spindle-shaped nanoparticles – was able to effectively target tumour cells when injected into mice.
“These nanoparticles are designed to overcome the dual challenges of effectively killing [glioblastoma] cells and efficiently penetrating the brain,” the team said in a paper published in the August issue of the peer-reviewed journal, Small Science.
These spindle-shaped nanoparticles have a diameter of just 50 to 80 nanometres and a length of around 170 nanometres. A nanometre is one-millionth of a millimetre – an average sheet of paper has of thickness of around 100,000 nanometres.
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>A new nanoparticle treatment is showing promise for glioblastoma, one of the most aggressive forms of brain cancer
>A new plant-based nanoparticle treatment for glioblastoma, the fastest growing and most aggressive form of brain cancer, has been developed by scientists in China and the US.
>Researchers from Renmin Hospital of Wuhan University and Yale University found that bardoxolone methyl (BM) – a phytochemical capable of self-assembly into spindle-shaped nanoparticles – was able to effectively target tumour cells when injected into mice.
>“These nanoparticles are designed to overcome the dual challenges of effectively killing [glioblastoma] cells and efficiently penetrating the brain,” the team said in a paper published in the August issue of the peer-reviewed journal, Small Science.
>These spindle-shaped nanoparticles have a diameter of just 50 to 80 nanometres and a length of around 170 nanometres. A nanometre is one-millionth of a millimetre – an average sheet of paper has of thickness of around 100,000 nanometres.
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