Free roaming spike proteins are dangerous. It's just that nobody has found a trace of them roaming free yet. Nobody can proof that they don't do it (maybe they only do it if nobody looks), but I would assume that the people who claim that they do it are the ones that have to proof their theory first. If somebody refutes the toxicity of spike proteins, they have not read the study that showed that while the whole spike protein is not toxic, the S1 part is really dangerous. The spike protein consists of two parts, called S1 and S2. S1 binds to ACE2, then a molecule that resides on the cell surface splits the spike protein and the S2 part fuses with the cell membrane, sucking the whole virus with it into the cell. If a solo spike molecule (without a virus attached) binds to ACE2, S2 gets split off and S1 remains. Sooner or later the cell will suck the ACE2 receptor in (to replace it with a new one). The attached S1 is so toxic that it kills the cell. > The Japan study link. https://archive.is/En79Q (archived - original: https://www.docdroid.net/xq0Z8B0/pfizer-report-japanese-government-pdf - annoying ads).