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(Bloomberg) -- In a real-world study of people with Covid-19, Pfizer Inc.’s antiviral Paxlovid was less effective at preventing the infection’s most serious cases than it was in initial trials.

The pill was just 37% effective at preventing hospitalization or death in high-risk patients when compared to no Covid treatment at all, according to an observational study published Thursday in JAMA Network Open. In earlier studies, it cut the risk of hospitalization or death by as much as 89%. . . .

>(Bloomberg) -- In a real-world study of people with Covid-19, Pfizer Inc.’s antiviral Paxlovid was less effective at preventing the infection’s most serious cases than it was in initial trials. >The pill was just 37% effective at preventing hospitalization or death in high-risk patients when compared to no Covid treatment at all, according to an observational study published Thursday in JAMA Network Open. In earlier studies, it cut the risk of hospitalization or death by as much as 89%. . . . [Source Article](https://www.msn.com/en-us/health/medical/paxlovid-is-now-less-effective-against-covid-study-shows/ar-AA1h3Pd8)

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Yeah, from what i've seen it's just like most illness/ colds/ flues - some people get it really bad others not so much. So yeah genetic/ and immune system not able to kick in strongly? - immune system response is hugely influenced by diet and overall general well-being and mental health - not suggesting anyone that gets really sick necessarily has a bad diet or is depressed. I guess it's kinda like how some people could chain smoke their entire life and never get (lung/ throat) cancer -My Father died well into his 80's - still chain smoking - worked 5-6 days a week until he retired and had maybe 4 days off in his entire life. as i already mentioned older brother - doesnt smoke rarely drinks - bowel cancer at 55 .

Now she has memory problems, nothing major but she’ll ask the same question each day, remembers important stuff but not minor stuff. It’s like she’s not fully there to have a conversation with. If you tell her a story unless it’s significant she won’t remember it and just says she’s 83.

Sounds very similar to my Mother, rapid marked memory decline, then after we noticed and night and day difference with overall cognitive ability 6 months later..

Unfortunately, my sister at the recommendation of GP got her boosted again at the start of this year (4th total) - three weeks later in and out hospital with sudden onset ALS - throat muscles no longer respond properly, basically they have difficulty via 'forgetting' to breath and can't chew food or swallow) gone 2 months later. Totally nothing to do with the vaxx - she 'simply passed from old age and heart failure'.

Be well. All the best to your Family.