Being Pilled is a slang drug term meaning they've consumed a drug. Black Pilled - Black is night time, you black out, etc. So, Black Pilled means you've taken a downer or sedative type drug. White Pilled - Cocaine is the most well known upper, high energy drug, and it's white. So White Pilled means you've taken a drug that gives you energy. Red and Blue Pilled - Red Pilled - Red is the feminine color. So drugs that make them feminine. Testosterone blockers, estrogen pills, etc. Blue Pilled - Blue is the masculine color. So testosterone, viagra, etc. Also, viagra pills are blue.