Having them everywhere does complicate things. I've run into situations where having far-flung workers can cause issues, especially if they need resources on company provided computers that's not easily installed via a remote session.
Some software is just shit and is a pain to install when you have the machine in front of you. Autodesk, I'm looking at you.
Not sure when the last time you installed Autodesk stuff, but they handle it like Adobe now. They sign into a general Autodesk cloud application, then pick what they want to install and it does the install for them. Aside from creating accounts you don't even have to mess with it anymore. Most users that are going to be using AutoCAD are smart enough to figure it out themselves. Most.
Oh, and even though it's cloud based they STILL audit you.
We still have old perpetual licenses that they would love for us to give up and convert to SaaS licenses.
Our IT director has told them in no uncertain terms where they may take those licenses and what they may do with them.
Good luck keeping them. They told us our perpetual 2016 version was going EoL and support was going to be like 4 times what the new cloud offering was going to cost.
Even still, we're on a grandfathered rate with our account which gives a substantial discount.
Oh, I am very, very, well aware of that. I have had to deal with that in multiple companies but there is always a way. It can be complicated to start but remote support tools bridge the gap. I have one that I self-host that I use to help Friends/Family now.
Its not as polished as a tool from some company but I know that (our) systems are not connected to someone-elses-computer that can in some situations grant full control of the system. It is also only online when needed. It would be a perfectly fine tool to admin remote employee systems unless they truly screw it up in a stupid way but even then most if not nearly all of the data should be remote.
I look at remote employee stations as disposable and all of the real data/work/etc is on a remote system (with a proper backup system in place). Sure, you might lose a employee for a few days if things go sideways but its better to have a system that does not rely on "it works on my computer" (I am looking at you, programmers... (Rage emoji) seriously...)