A cheeky answer could be that you'd need to locate the designer for a answer to that question.. If everything was known to us on how nature works, the question could be answered generally, but it's not, so it can't. Changes in "design" can be observed looking at phossilized remains of certain species, existing in the same place at different ages, where the environment has undergone change. You may be able to make a map or blueprint if you will, of possible adaptive measures that nature *might* apply to some form or state of being in a known environment and calculate the likely outcome of specific change to that. While the mechanisms and laws of nature are relatively well known, they're also wildly unpredictable and measures or counter-measures to change, is not per definition obvious, as i understand it..