This is how the information is developed. If you focus on this limited window and some kid dies losing 60-70 years of expected life it drags down the average. It's hard to understand the whole impact so early, but yes, it is a life shortening treatment for some. When they looked at the mRNA persisting in the body I think the first result was 28 days or so for some. We are now to 1800 days for some and it keeps going up.