Posting to vax because it is relevant to [vax discussion for monkeypox shots.](https://poal.co/s/Vax/725002) This from Peter McCollugh substack which is paywalled >A report by Kannan et al, indicated that what happened in 2022 almost certainly occurred because of a gain-of-function mutation in one or more genes within the Monkeypox virus. The authors do not speculate on whether this happened in a laboratory or in nature. DNA virus does not mutate into a new disease after a couple years. This was done in a lab.