Welcome • User Guide
ToS • Privacy • Canary
Donate • Bugs • License

©2024 Poal.co

780

Source (pubchem.ncbi.nlm.nih.gov)

Archive (archive.ph)

[Source](https://pubchem.ncbi.nlm.nih.gov/patent/US-11229693-B2) [Archive](https://archive.ph/B3hg7)
You are currently inside a comment thread.
Click here to see all the comments (13).
[–] • 0 pt (edited )

lol Seriously? It's right in front of your eyes.

Poxvirus vectors encoding HIV antigens

1 Abstract

Poxvirus vectors encoding a synthetic HIV envelope antigen and other HIV antigens, as well as compositions containing such poxvirus vectors and uses of such poxvirus vectors as vaccines to provide improved immunity against HIV, are provided. Also provided are vaccine combinations containing the disclosed poxvirus vectors, adenovirus vectors encoding one or more HIV antigens, and one or more isolated HIV antigenic polypeptides, and methods of using the vaccine combinations to provide improved immunity against HIV.

[–] • 1 pt (edited )

I'm with @doginventor in this.

The antigens proto-antigens are HIV but they use pox as a vector bug to insert the HIV protein encoding DNA into the cell nucleus. It is a DNA vaccine for HIV.

The virus of a viral vector vaccine is not the vaccine antigen. You did not get an adenovirus benefit from AZ/JJ. You will not get a pox benefit from this one.

[–] • 0 pt

N.B it’s doginventer [not doginventor - (thanks AOU)] :)

[–] • 0 pt

… and methods of using the vaccine combinations to provide improved immunity against HIV.

It doesn’t mention Monkeypox anywhere. In fact is specifically states that it is targeting HIV.
I’m not in any way discounting the idea that what you say is true but the patent only mentions HIV and pox/poxvirus.
Poxviruses: “ Poxviridae is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox.[1][2] Poxviridae Virus classification Edit this classification (unranked): Virus Realm: Varidnaviria Kingdom: Bamfordvirae Phylum: Nucleocytoviricota Class: Pokkesviricetes Order: Chitovirales Family: Poxviridae Subfamilies See text Four genera of poxviruses may infect humans: Orthopoxvirus, Parapoxvirus, Yatapoxvirus, Molluscipoxvirus. Orthopoxvirus: smallpox virus (variola), vaccinia virus, cowpox virus, Mpox virus; Parapoxvirus: orf virus, pseudocowpox, bovine papular stomatitis virus; Yatapoxvirus: tanapox virus, yaba monkey tumor virus; Molluscipoxvirus: molluscum contagiosum virus (MCV).[3] The most common are vaccinia (seen on the Indian subcontinent)[citation needed] and molluscum contagiosum, but Mpox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster.
Poxviridae - Wikipedia https://en.wikipedia.org/wiki/Poxviridae