When I found out in the early 2000’s former pharma executives were on the approval panel I knew it was corrupt. When my dad got sick they’d only use monotherapy, when it’s proven cocktail therapy works a lot better by blocking multi pathways. His doctor agreed but his hands were tied” this is the approved therapy”. We got multiple doctors, paid out of pocket and at the time he was the longest living cancer patient with his form of cancer. His doctor was amazed but still couldn’t do the therapy under insurance since no trials had been conducted. But aids patients get 30 drugs that costs 100’s of thousands a year to prevent viral escape but not cancer patients. There was also a drug that worked better then viagra, worked on people that viagra failed, it was cheaper also. One old go got low blood pressure in the phase 3 trial and it was nixed. Never mind viagra gives heart attacks. I lost a ton on that stock.