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Published Volume 5 | Issue 1 | 1 of 3 Microbiol Infect Dis, 2021

Abstract

Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARS-CoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. In the current analysis a total of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. This interaction has the potential to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.

Published Volume 5 | Issue 1 | 1 of 3 Microbiol Infect Dis, 2021 **Abstract** Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARS-CoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. **The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations.** I*n the current analysis a total of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified*. Two GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. *This interaction has the potential to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic prion configuration*. **The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases**. The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that **the vaccine may cause much more harm than benefit**.

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[–] • 0 pt (edited )

Almost, this will make you an expert and ease your worries.

Proteins don’t, viruses(and this vaccine) make proteins once inside your cell to create a brand new complete virus cell that hops to another healthy cell once it’s complete(to reproduce again) or gets shedded and someone else gets sick.

This happens with every virus you’ve ever caught or given to someone, you need the full virus for this to happen(or an experimental vaccine).

The simplest viruses contain only enough RNA or DNA to encode four proteins. The vaccine only makes 1(the spike protein(not the complete virus), which is dangerous to the person receiving the vaccine as seen below.

The person coming into contact with the spike protein second hand from shedding doesn’t run a risk of this problem since the spike protein can only attach to a cell and can’t replicate on it own, it also doesn’t contain the rna to replicate. As I stated before you may feel a little under the weather at tops but you’ll get over it shortly, the shedder won’t.

they did not find full-length viral RNA integrated into genomic DNA; rather, they found smaller segments of the viral DNA, mostly representing the nucleocapsid (N) protein of the virus, although other viral segments were found integrated into human DNA at a lower frequency.

The MIT study was looking at why some people were still testing positive months later after recovering, they found the N protein had gotten hard coded into their DNA (MSM and the usual sources “debunked” it immediately). For the vaccinated the antibody test would have to be changed to check for the Spike protein. Also the spike protein is magnitudes more dangerous since your body knows exactly what a spike protein is and will mount massive attacks against it.

the RNA in the vaccine is a different animal than the RNA produced by the virus. The RNA in the vaccine is artificially engineered. First, it is engineered to stay around in your cells for a much longer time than usual (RNA is naturally unstable and degrades quickly in the cell). Second, it is engineered such that it is efficient at being translated into protein (they accomplish this by codon optimization). Increasing the stability of the RNA increases the probability that it will become integrated into your DNA; and, increasing the translation efficiency increases the amount of protein translated from the RNA if it does happen to become incorporated into your DNA in a transcriptionally active region of your genome.

As a side note, these researchers found that the genetic information for the nucleocapsid “N” protein was, by far, the largest culprit for being permanently integrated into human DNA (because this RNA is more abundant when the virus replicates in our cells). The vaccine, on the other hand, contains RNA that encodes the Spike (S) protein. Therefore, if the mRNA from the vaccine (or subsegments thereof) were to make its way into a transcriptionally-active region of our genome through a retro-integration process, it will cause our cells to produce an over-abundance of Spike protein, rather than N protein. Our immune system does make antibodies to both N and S proteins, but it is the Spike protein which is the prime target for our immune system because it exists on the outside of the virus. If our cells become permanent (rather than temporary) Spike Protein producing factories due to permanent alteration of our genomic DNA, this could lead to serious autoimmune problems.

first let’s just address the big elephant in the room first. First, you should care because, “THEY TOLD YOU THAT THIS WAS IMPOSSIBLE AND TO JUST SHUT UP AND TAKE THE VACCINE.” These pathways that I hypothesized (and these researchers verified with their experiments) are not unknown to people who understand molecular biology at a deeper level. This is not hidden knowledge which is only available to the initiated.  I can assure you that the people who are developing the vaccines are people who understand molecular biology at a very sophisticated level.  So, why didn’t they discover this, or even ask this question, or even do some experiments to rule it out? Instead, they just used superficially simplistic biology 101 as a smoke screen to tell you that RNA doesn’t convert into DNA. This is utterly disingenuous, and this lack of candor is what motivated me to write my original article.  They could have figured this out easily.

Second, there’s a big difference between the scenario where people randomly, and unwittingly, have their genetics monkeyed with because they were exposed to the coronavirus, and the scenario where we willfully vaccinate billions of people while telling them this isn’t happening. Wouldn’t you agree? What is the logic in saying, “Well, this bad thing may or may not happen to you, so we’re going to remove the mystery and ensure that it happens to everyone.”? In my best estimate, this is an ethical decision that you ought to make, not them.

[–] • 0 pt

Thanks. One more question, what are the repercussions for someone who has recovered from the "natural" virus and now has the N protein recipe integrated into their DNA? And what do you think would happen if such a person is then exposed to the vaccine?