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This will be interesting. I take Dupixent for atopic dermatitis. Dupixent is a monoclonal antibody. Works ok but has a couple of side effects. Nothing bad just noticeable

This will be interesting. I take Dupixent for atopic dermatitis. Dupixent is a monoclonal antibody. Works ok but has a couple of side effects. Nothing bad just noticeable

(post is archived)

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The crazy thing is everything is on “prevention”, Fauci is being criticized for antiviral development and vaccines when the real cause of deaths are cytokines storms.

Solve that and you’ve just saved flu patients also, it’s not as hard as developing vaccines, there’s already current medications out there that can do this in combination with corticosteroids, the military is using Humira and I’m sure other drugs could be repurposed.

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The cytokine storm is one killer, the other one is blood clotting. Vitamin D taken early can prevent the cytokine storm. Ivermectin does not only reduce the virus load, it also regulates the immune response in late stages. Azithromycin too. And, of course, corticosteroids. The blood clotting is caused by oxidative stress - melatonin, NAC and vitamin C IV help. Blood clotting is also caused by one kind of antibodies produced against the spike protein, they bind to platelets and activate their aggregation - heparin helps.

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Only IV vitamin c works?

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The ACE2 that is attacked by the virus is an enzyme that produces stuff that lowers oxidative stress. The missing stuff can get replaced with melatonin, NAC and glutathione. Vitamin c lowers oxidative stress too, but only in very high dosage - nothing the stomach can stand.

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Does fucking hydroxychloroquine work or not? Seems like everything these other drugs do it does it just as well and fights inflammation big time which is the killer in the lounges

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Ivermectin works even better. But DeSantis has to use something that is FDA approved. It's up to the FDA to approve already known medications, and of course they didn't - approving a drug means invalidating the emergency approvals for the vaccines. The monoclonal antibody cocktails were especially made for C19, so the FDA was forced to consider them for approval. They dragged it out, demanding one trial after another, but the results were so overwhelming that they finally had to approve it. They have found a trick to avoid the invalidation of the vaccine approvals: They approved the antibodies only for "high risk" patients.

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These are different antibodies, antibodies are specialized so Dupixent doesn't help against SARS 2. The virus has maybe 1,000 different points where antibodies can dock to. The immune system does not create all of the possible antibodies, there is some random factor, and some antibody types are sorted out because they also bind to human tissue. The manufacturers of the monoclonal antibodies try to identify one of the most effective antibody type ("neutralizing" antibody), they try to make sure they don't bind elsewhere, and they make sure that the targeted part of the virus doesn't mutate much (so that variants cannot evade). Some manufacturers mix two or more different antibodies ("polyclonal antibody cocktail").

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Seems they’re mixing to with Regeneron.

casirivimab and imdevimab