Ugh boomer parents. Mothers can be far worse than abusive fathers with endless enabling. It sounds like she wears the pants and your father just goes along with it.
Without writing a novel on this it comes down to education. Everyone involved needs to become a competent psychologist or get the fuck out of the way completely, this includes your brother. More to the point your brother needs to want to get better and to make it worse it sounds like he's still well into that phase where it all seems hopeless and doomed no matter what he does. The best thing for this is usually a detox from drugs but also environment. As an example, but likely unrealistic,... Stick him on a plantation/farm in some third world country where living requires a full day full of chores like chopping wood, butchering and cooking. The work help distract the mind and makes the days shorter. He'd be completely removed from online and any "friends" he has that are just as fucked up as he is. The people there will be much healthier as an influence for him and will give him a better status quo to try and adapt to. A situation like that would help him get a better perspective on what's actually possible for him and what he can look forward to.
It's a long road and unfortunately most people in his life, yourself included, will only make it worse while trying to make it better.
Stick him on a plantation/farm in some third world country where living requires a full day full of chores like chopping wood, butchering and cooking.
I could use one of these... as a vacation.
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