The danger seems to be eliminating things that are important but not easily measured or not recognized as important, since genes have wide-ranging effects (I don't think you can just increase muscle tone without effect on anything else).
I absolutely agree in general, but in the case of muscle tone there are multiple other mammals with exact mutation I'm talking about and at most it seems to shave months of their life cycles but bit even a full year and, its a beneficial adaptation from what we've seen in wild kangaroos however we cant gauge intellect well in the species it occurs in but I believe testing on genetically modified apes and monkeys is underway.
The issue with muscle tone is imagine those ripped pitbulls, kangaroos, rats, cats, and gorrilas and then imagine a woman with it, it isn't worth introducing in a way that it could effect women in the future.
There are also some questions about what happens to smooth muscle when this specific gene is altered.
It may be more beneficial to collect the correct genes to alter ligature attachments and vascular diameter in concert with those bowl shaped blood cells and simple exclude the muscle tone gene.
Research must be done and imho this requires human experimentation, biotech firms doing this need to provide for these people for life regardless of complications as the experiments require a child be born and grow into adulthood without complications to count as a safe sample.