Yup, I've been a D3 (~3000mg/day) & zinc advocate long before the stupidity of the last 2 years, and had been exploring the line of thought that more magnesium in my diet might displace or "out-compete" the uric/oxalic acid in my joints, but after reading through a couple of pages on K2 (and the positive and negatives of K1) it was an absolute lightbulb moment for me. (I'll be sticking with the magnesium and throw in some omega-3's too, of course.)
You might want to have your homocysteine levels checked too. High homocysteine may be an indication of the MTHFR gene defect:
" ....oxalate problems create low sulfate issues, it becomes clear that individuals with MTHFR and related gene SNPs will also suffer. MTHFR and methylation cycle pathways help the body to grow, repair, and detoxify all sorts of compounds. When oxalate levels are high, sulfate levels drop slowing down detoxification. Low sulfate levels put extra stress into the methylation cycle to provide the body with sulfate molecules. In individuals with an impaired methylation cycle this can provoke methylation issues such as high homocysteine, developmental disorders, gallbladder dysfunction, hormone imbalances, excess inflammation, poor growth and to name but a few. So with oxalate issues and the biochemical chaos it creates, a great deal of stress is placed on the methylation cycle (an important component of the metabolic cycle)."
Now kiss.
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