International Journal of Vaccine Theory, Practice, and Research 2 (1), May 10 , 2021 Page | 402 Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID - 19

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I mean...... I guess.

It is a very detailed and pretty exhaustive review of the current covid vaccines which covers:

Vaccine Development (including description of previous attempts of vaccine development and the exceptionally low chance of success of passing clinical trials for vaccines using unprecedented technology, compared to with the emergency use authorization and lack of safety data for both vaccines being used in the USA), (including questioning the claims of 90-95% efficacy of these vaccines which appear to have cherry picked data alongside the unexplained breakthrough cases where vaccinated individuals still test positive for covid), including what part of the immune response is stimulated, how long this effect and other side effects may be present in the system, and how efficacious it may be for future mutations of covid.
Technology of mRNA vaccines (including the unknown consequences of introducing foreign mRNA into human cells, how long the spike protein being displayed on affected cells persists, and the unknown consequences of genetically altering portions of the mRNA to promote the production of a significantly greater abundance of the protein than would normally be generated (in an attempt to elicit a robust immune response), (including that the delivery vehicle used (lipid nanoparticles) are engineered to be extremely efficient at protecting the RNA from degradation--but concurrently they increase the release of pro-inflammatory molecules by antigen presenting cells (which do not only remain local but enter the systemic lymphatic system) and this could be responsible for many of the adverse symptoms people experience from vaccination), (including the presence and role of the adjuvents (additives intended to direct the immune response) of each vaccine, their mechannisms, and their potential to cause adverse health effects (anaphylaxis was discussed specifically)
Antibody-Dependent Enhancement i.e. when low levels of antibodies which are present (either due to previous viral infection, exposure to a related virus, or previous vaccination) which either are not numerous enough to neutralize a current viral infection or are not potent enough (due to lack of specificity to the current infection) to neutralize the current viral infection, however they do bind to the virus in a way that facilitates the virus to enter the cells and increases overall viral infectivity. It discusses previous vaccination campaigns and development attempts where this has occurred.
Pathogenic Priming Discussion that high levels of cross reactive antibodies against endogenous human proteins are present, and questions the potential for auto-immune disease development. Emphasizes that antibodies with a high binding affinity to SARS CoV 2 spike and other proteins also have a high binding affinity with tTG (associated with Celiac Disease), TPO (Hashimoto’s thyroiditis), myelin basic protein (multiple sclerosis), and several endogenous proteins. Unlike the autoimmune process associated with pathogen priming, these autoimmune diseases typically take years to manifest symptomatically. Reviews multiple studies from 2020 which investigate this potential phenomenon.
The Spleen, Platelets, and Thrombocytopenia Reviews blood clotting issues reported following vaccination and discussed the potential inflammatory response in the spleen reviews studies looking at impaired platelet production due to pro inflammatory signaling cascade resulting in suppression of production of megakaryocytes (the precursors to platelets). Other various clotting concerns in the spleen.

Ok i'm tired and ready to quit now so thats pages 1-19. There are 29 readable pages (and like 13 pages of references). You can read on for things like activation of herpes zoster (i'm surprised they didn't include anything on development of bells palsy here), potential for spike protein toxicity to human tissues (since vaccines are making a ton of it), possible linkages to prion disease and neurodegeneration, potential for permenant integration of RNA into DNA, potential for spike protein shedding, etc.

It is a great paper i think because it is very cut and dry factual information and raises reasonable questions.

I mean...... I guess. It is a very detailed and pretty exhaustive review of the current covid vaccines which covers: - **Vaccine Development** (including description of previous attempts of vaccine development and the exceptionally low chance of success of passing clinical trials for vaccines using unprecedented technology, compared to with the emergency use authorization and lack of safety data for both vaccines being used in the USA), (including questioning the claims of 90-95% efficacy of these vaccines which appear to have cherry picked data alongside the unexplained breakthrough cases where vaccinated individuals still test positive for covid), including what part of the immune response is stimulated, how long this effect and other side effects may be present in the system, and how efficacious it may be for future mutations of covid. - **Technology of mRNA vaccines** (including the unknown consequences of introducing foreign mRNA into human cells, how long the spike protein being displayed on affected cells persists, and the unknown consequences of genetically altering portions of the mRNA to promote the production of a significantly greater abundance of the protein than would normally be generated (in an attempt to elicit a robust immune response), (including that the delivery vehicle used (lipid nanoparticles) are engineered to be extremely efficient at protecting the RNA from degradation--but concurrently they increase the release of pro-inflammatory molecules by antigen presenting cells (which do not only remain local but enter the systemic lymphatic system) and this could be responsible for many of the adverse symptoms people experience from vaccination), (including the presence and role of the adjuvents (additives intended to direct the immune response) of each vaccine, their mechannisms, and their potential to cause adverse health effects (anaphylaxis was discussed specifically) - **Antibody-Dependent Enhancement** i.e. when low levels of antibodies which are present (either due to previous viral infection, exposure to a related virus, or previous vaccination) which either are not numerous enough to neutralize a current viral infection or are not potent enough (due to lack of specificity to the current infection) to neutralize the current viral infection, however they do bind to the virus in a way that facilitates the virus to enter the cells and increases overall viral infectivity. It discusses previous vaccination campaigns and development attempts where this has occurred. - **Pathogenic Priming** Discussion that high levels of cross reactive antibodies against endogenous human proteins are present, and questions the potential for auto-immune disease development. Emphasizes that antibodies with a high binding affinity to SARS CoV 2 spike and other proteins also have a high binding affinity with tTG (associated with Celiac Disease), TPO (Hashimoto’s thyroiditis), myelin basic protein (multiple sclerosis), and several endogenous proteins. Unlike the autoimmune process associated with pathogen priming, these autoimmune diseases typically take years to manifest symptomatically. Reviews multiple studies from 2020 which investigate this potential phenomenon. - **The Spleen, Platelets, and Thrombocytopenia** Reviews blood clotting issues reported following vaccination and discussed the potential inflammatory response in the spleen reviews studies looking at impaired platelet production due to pro inflammatory signaling cascade resulting in suppression of production of megakaryocytes (the precursors to platelets). Other various clotting concerns in the spleen. Ok i'm tired and ready to quit now so thats pages 1-19. There are 29 readable pages (and like 13 pages of references). You can read on for things like activation of herpes zoster (i'm surprised they didn't include anything on development of bells palsy here), potential for spike protein toxicity to human tissues (since vaccines are making a ton of it), possible linkages to prion disease and neurodegeneration, potential for permenant integration of RNA into DNA, potential for spike protein shedding, etc. It is a great paper i think because it is very cut and dry factual information and raises reasonable questions.

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[–] • 0 pt

Excellent.

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