This is interesting. I just skimmed the article, as most of it was over my head. What little I know: Schizophrenics are often chain smokers. The theory, if it is only a theory, is that the nicotine helps the brain. Niacinimide or nicotinic acid is ofter recommended to help heal their brains, and survive withdrawal from the psych drugs. It's been 10 years or so since I researched this. Dr. Peter Breggin wrote a book on this, but I no longer remember which book discusses it. https://livhealth.com/nicotinic-acid-benefits/ This was the first basic site I found on it.