Thanks, BioStud. (Your username has unfortunate initials ;-))
Please let us know if anything stands out in this vid as particularly significant.
Are you familiar with Dr. Shiva Ayyadurai? Here's his most recent commentary on vitamin D and the immune system. (youtu.be)
Both of them are right on the money, vitamin D is obnoxiously important, and plays an essential role in immune regulation. See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821804/
In pervious posts on voat, we had a good group discussion going about the corelation of Vitamin D signalling, and antioxidant levels, vitC, Selenium, zinc, etc. The CAMPs angle I wasn't familiar with, but it looks solid to me. Surprised they have both anti-bacterial, and viral activity! That's unusual, however even if that turns out to be a minor action, the steroid hormones all dimerize, in order bind to their HRE, with us staying inside so much, vitamin D levels likely are the bottleneck on a half dozen pathways trying to restore homeostasis.
People are sick at a physiological level, just most aren't sick enough to realize it. Vitamins and minerals matter!
Interesting indeed. (Had to look up 'dimerize'...been half a century since my last biochem class. ;-))
If you don't mind...what was your VOAT username?
Same name, I'm a creature of habit.
Nuclear receptors get complicated and highly specifical in a hurry. In general each one has a zinc finger motif that lets it recognize a short dna sequence, add so by having them mix and match into sets of two.. some things turn off, or turn on in a highly regulated manner.
Say, vitamin D + vitamin A receptor turns on YFP, while vitamin A+ Vitamin A only turns it off. Its complicated, and when it's out of balance, alternative pathways get activated that don't work as well. Combine a lifetime of neglect with a virus.... Yeah. It's an issue.
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