>>Egas Moniz introduced lobotomy, a surgical operation involving an incision into the prefrontal lobe to mitigate severe symptoms of serious mental illnesses. The operation was widespread during the 1940s and 1950s, but it became apparent that it could lead to serious personality changes. ****The use of lobotomies declined drastically when medications for mental illness were developed during the 1950s. https://www.nobelprize.org/prizes/medicine/1949/moniz/facts/ Honestly, looking at the world and history I bet it actually works when done correctly but one and done doesnt make as much money as taking drugs for life.