Archive: https://archive.today/lxzT7 From the post: >>Findings: In this pilot randomized clinical trial of 80 participants, none of the 6 coprimary outcomes reached the prespecified significance threshold; for verbal memory, scores declined by 1.42 points annually in the placebo group vs 0.73 points in the lithium group, which did not meet the prespecified threshold for multiple comparisons. Exploratory analyses suggested possible larger effects among amyloid-positive participants.