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Found out about this in Judy Mikovits's book, 'Plague of Corruption' (Chapter 'The Way Forward'). Very few seem aware of this study and this could help so many kids and their suffering parents.

Interview with Robert Naviaux, MD, PhD, professor of genetics in the departments of medicine, pediatrics and pathology

https://health.ucsd.edu/news/topics/suramin-autism/pages/q-and-a.aspx Edit: Direct link to PDF http://naviauxlab.ucsd.edu/wp-content/uploads/2016/06/Naviaux-QA-6-14-17-v24.pdf

The children begin to blossom. Children with severe oral motor dyspraxia in the SAT-1 study started humming and singing nonsense tunes around the house in the first few days after suramin. Like a baby learning to talk for the first time, they began making new sounds with their mouth, lips and tongue that they had never made before. We had four non-verbal children in the study, two 6-year-olds and the two 14-year-olds. The 6- and the 14-year-old who received suramin said the first sentences of their lives about one week after the single suramin infusion. This did not happen in any of the children given placebo.

https://health.ucsd.edu/news/topics/suramin-autism/pages/default.aspx Edit: Alt source https://journals.asm.org/doi/full/10.1128/AAC.01168-19

Suramin is a 100-year-old drug developed to treat African sleeping sickness and river blindness. Though it has been investigated for other diseases, including cancer, it is not approved for any therapeutic use in the United States.

However, a small, randomized clinical trial conducted by Robert Naviaux, MD, PhD , professor of medicine, pediatrics and pathology, and colleagues at University of California San Diego School of Medicine have found that a single intravenous dose of suramin produced dramatic, but transient, improvement of core symptoms of autism spectrum disorder.

Problem appears to be: Suramin is very old and off-patent. No money to be made. Its also virtually free of side effects. Reminds me of the whole Ivermectin debacle. Pharma would have to make a new, patentable variant in order to reap profits.

Regarding the "transient" nature of the improvements:

QUESTION: Will suramin need to be given for life?

ANSWER: I don't think so, but we don't have the science to answer this question yet. More studies will be necessary to see if improved development can become self-sustaining without the need for regular suramin treatment.

I only found it in IV / injectable form. Don't know if oral is available. https://www.rxlist.com/consumer_suramin/drugs-condition.htm

Found out about this in Judy Mikovits's book, 'Plague of Corruption' (Chapter 'The Way Forward'). Very few seem aware of this study and this could help so many kids and their suffering parents. Interview with Robert Naviaux, MD, PhD, professor of genetics in the departments of medicine, pediatrics and pathology https://health.ucsd.edu/news/topics/suramin-autism/pages/q-and-a.aspx Edit: Direct link to PDF http://naviauxlab.ucsd.edu/wp-content/uploads/2016/06/Naviaux-QA-6-14-17-v24.pdf >The children begin to blossom. Children with severe oral motor dyspraxia in the SAT-1 study started humming and singing nonsense tunes around the house in the first few days after suramin. Like a baby learning to talk for the first time, they began making new sounds with their mouth, lips and tongue that they had never made before. We had four non-verbal children in the study, two 6-year-olds and the two 14-year-olds. The 6- and the 14-year-old who received suramin said the first sentences of their lives about one week after the single suramin infusion. This did not happen in any of the children given placebo. https://health.ucsd.edu/news/topics/suramin-autism/pages/default.aspx Edit: Alt source https://journals.asm.org/doi/full/10.1128/AAC.01168-19 >Suramin is a 100-year-old drug developed to treat African sleeping sickness and river blindness. Though it has been investigated for other diseases, including cancer, it is not approved for any therapeutic use in the United States. > However, a small, randomized clinical trial conducted by Robert Naviaux, MD, PhD , professor of medicine, pediatrics and pathology, and colleagues at University of California San Diego School of Medicine have found that a single intravenous dose of suramin produced dramatic, but transient, improvement of core symptoms of autism spectrum disorder. Problem appears to be: Suramin is very old and off-patent. No money to be made. Its also virtually free of side effects. Reminds me of the whole Ivermectin debacle. Pharma would have to make a new, patentable variant in order to reap profits. Regarding the "transient" nature of the improvements: > QUESTION: Will suramin need to be given for life? > ANSWER: I don't think so, but we don't have the science to answer this question yet. More studies will be necessary to see if improved development can become self-sustaining without the need for regular suramin treatment. I only found it in IV / injectable form. Don't know if oral is available. https://www.rxlist.com/consumer_suramin/drugs-condition.htm

(post is archived)

[–] 0 pt

Strange. Most *.uscd.edu subdomains seem to be up, but it's hit and miss. Their site is an unholy mess.

I've sampled some from their index: https://ucsd.edu/about/a-to-z-index/index.html

A few non-responsive sites: Autism Center of Excellence - 404 http://www.autism-center.ucsd.edu/

Archives - Not found http://libraries.ucsd.edu/collections/sca/collections/ucsd-archives.html

Health Sciences Faculty Council - Busy https://medschool.ucsd.edu/vchs/faculty-academics/faculty-council/Pages/default.aspx

Couldn't search in e.g. archive.ph because they too seem down atm.

Searched for Suramin in their Library: https://search-library.ucsd.edu/discovery/search?query=any,contains,suramin&tab=ArticleBooksEtc&search_scope=ArticlesBooksEtc&vid=01UCS_SDI:UCSD&offset=0 Screen shot: https://pic8.co/sh/skOuqD.png

The naviauxlab subdomain currently still has the trial PDF: http://naviauxlab.ucsd.edu/wp-content/uploads/2016/06/Naviaux-QA-6-14-17-v24.pdf

The '100 Years of Suramin' article is still available here: https://journals.asm.org/doi/full/10.1128/AAC.01168-19