As further search for effects on health of consuming more I stumbled on this article. Can anybody here help with the medical jargon, thank you:
Coffee and its components did not repair the altered levels of Gram-positive and Gram-negative bacteria and an increased abundance of Firmicutes in TSOD mice but rather caused additional changes in bacteria in six genera.
...so then lack of SCFA does not necessarily mean there is a microbiome unbalance, you can have skewed microbiome but SCFA profile can be fine?
In addition to functioning as an energy substrate, SCFAs affect several physiological processes of the hosts’ tissues and organs by modulating anti-inflammatory responses and neuroendocrine system
...looks like promoting SCFA in the gut has all kinds of health benefits stemming from reducing soft tissue inflammation?
Daily intake of coffee or major coffee components prevented hepatic lobular inflammation in TSOD mice
...TSOD mice r supposedly prone to spontaneous beetus? Comparable to prediabetics? What is hepatic globular inflammation?
The most plentiful product of undigested dietary fibers by bacterial fermentation are 1–6 carbons-containing short-chain fatty acids (SCFAs) which link gut microbiota and the host’s physiology.
...does this mean to say that dietary fibers should not be fermented in the gut in order to promote higher levels of SCFA in the gut? From what I've been reading we need more SCFA...
As further search for effects on health of consuming more [Chlorogenic acids,](https://poal.co/s/Health/513787) I stumbled on this article. Can anybody here help with the medical jargon, thank you:
> Coffee and its components did not repair the altered levels of Gram-positive and Gram-negative bacteria and an increased abundance of Firmicutes in TSOD mice but rather caused additional changes in bacteria in six genera.
...so then lack of SCFA does not necessarily mean there is a microbiome unbalance, you can have skewed microbiome but SCFA profile can be fine?
> In addition to functioning as an energy substrate, SCFAs affect several physiological processes of the hosts’ tissues and organs by modulating anti-inflammatory responses and neuroendocrine system
...looks like promoting SCFA in the gut has all kinds of health benefits stemming from reducing soft tissue inflammation?
> Daily intake of coffee or major coffee components prevented hepatic lobular inflammation in TSOD mice
...TSOD mice r supposedly prone to spontaneous beetus? Comparable to prediabetics? What is hepatic globular inflammation?
> The most plentiful product of undigested dietary fibers by bacterial fermentation are 1–6 carbons-containing short-chain fatty acids (SCFAs) which link gut microbiota and the host’s physiology.
...does this mean to say that dietary fibers should not be fermented in the gut in order to promote higher levels of SCFA in the gut? From what I've been reading we need more SCFA...
(post is archived)