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[–] 0 pt

I thought the mechanisms of action were acting like a zinc ionophore, as well as a protease inhibitor.

[–] 0 pt

Ivermectin has a lot of mechanisms of actions that work against SARS-2. Maybe working as a zinc ionophore is one of them, but Quercetin and HCQ can do that much better.

The most important MOA is that Ivermectin blocks importins (https://pubmed.ncbi.nlm.nih.gov/32135219/). Importins are used by the virus to send stuff into the nucleus of infected cells that block the gene expression needed for the defence. Nothing can be more important than restoring the self-defence mechanisms of the body.