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In its BNT162b2/Comirnaty Risk Management Plan submitted to the FDA to get Emergency Use Authorization, Pfizer admits that the codon optimization they did resulted in elevated gamma-glutamyl transferase (GGT), which is an early marker of heart failure.

>In its BNT162b2/Comirnaty Risk Management Plan submitted to the FDA to get Emergency Use Authorization, Pfizer admits that the codon optimization they did resulted in elevated gamma-glutamyl transferase (GGT), which is an early marker of heart failure.

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Any reference for an explanation of the mechanism? I know what codon optimization is and I don't see how it could cause heart attacks on its own.