Good to know. https://www.cell.com/cell/fulltext/S0092-8674(22)00076-9 explains that one of the problems mRNA vaccines had to solve was that cells detect the alien RNA and destroy it. They solved it by replacing one of the building blocks with an analog one, which is not used by nature. This means that not only the friend-foe detection gets tricked, but also all the enzymes that make RNA short lived.
Good to know. https://www.cell.com/cell/fulltext/S0092-8674(22)00076-9 explains that one of the problems mRNA vaccines had to solve was that cells detect the alien RNA and destroy it. They solved it by replacing one of the building blocks with an analog one, which is not used by nature. This means that not only the friend-foe detection gets tricked, but also all the enzymes that make RNA short lived.
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