No one knows. Everything is a give or take. TRT will reduce risk of diabetes, increase cognition, lower BF % stronger (who cares when ur older), etc. It will also increase your chance of a heart attack and stroke due to thickened blood, higher BP, etc. If you have family history of hypercholestemia, and issues like this - i'd be more concerned about being low body fat/BMI 10-12 etc. IMO, you are better off losing fat even if it's harder at lower T rather than risk this in old age. It's a wash with pros/cons but I think it's better to not take it. Plus when you go on it long enough you may permanently need to take it exogeneously and you can also fuck up your fertility if you want kids (then have to take HCG or Clomid or other weird drugs). a