Natural chemistry, quite literally, you are what you eat. Eat right, know the chemistry in your food and drinks. Supplement with vitamins, minerals, and enzymes. It sounds hard, but it's not, once you learn what is going on with the food and water. Your natural state is to be healthy and happy, generally, all the time. With a healthy state of mind. That happens automatically once you purge all of the crap out of your system, and give your body the right chemistry. Think of it as putting the right gasoline in your car. What happens to your car with the wrong gasoline? At a minimum it gets very cranky. Also, get some more exercise. Exercise is a weapon that improves your body, improves your chemistry, and improves your life. Yes it's hard, but becoming good at doing hard things reinforces your own self worth in an undeniable way. Dedicate yourself to anything for 60 months and you should become pretty good at it. 60 months is about the same as a master's degree in university.