yes you would want to know the entire genomic sequence of a virus to target specific parts of the genome and avoid off target effects. when selecting primers and guide RNAs for CRISPR you need to target a unique sequence. the only way to ensure you're targeting a unique sequence is to look in the entire genome.
isolating and sequencing an entire viral genome is not difficult though. it's routine
yes you would want to know the entire genomic sequence of a virus to target specific parts of the genome and avoid off target effects. when selecting primers and guide RNAs for CRISPR you need to target a unique sequence. the only way to ensure you're targeting a unique sequence is to look in the entire genome.
isolating and sequencing an entire viral genome is not difficult though. it's routine
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