The main concern is the spike protein as a pseudo prion in genetically modified humans creating an auto immune disorder in people exposed to the spike protein, this is why unvaxxed women are reporting miscarriage's and heavy periods. Spike protein is a master key for the cells with ACE2 expression, this is how the body of a corona virus enters your cells and hijacks it's reproductive functions to produce copies of itself, the spike protein is bound to the outer body of the corona virus, which is also made up of a similar molecule chain to those sorts of cells which have ACE2 expression, this is how the spike protein is bound to the SARS virus in the first place. Loose spike protein in the blood will end up binding to ACE2 expressed cells and "opening" them, parts of your immune system will see the S protein bonded to the cell, presume an infection is ongoing and begin attacking the effected cells. In a normal infection the viral body is identified and antibodies which may do anything from close or kill your own cells or have chemical properties which viruses bind to and are made inert, the other is killer T cells but killer T cells are like little viral hunters that are sort of trained through natural selection to identify some element of the infection and to attack, they are good at identifying foreign bodies within larger cells, then they kill the effected cell, the issue with the t cells is that they are often associated to auto immune problems because they can misidentify a symptom as a cause or trigger a general immune response on a non emergency. An aside, I'm allergic to grass* and tobacco smoke, I had a bad case of pneumonia as a toddler and the two were present throughout my prolonged illness, CIS-3-Hexenal is the pheromone grass releases when damaged an aldehyde compound similar to those in cigarette smoke and the waste compounds let off by many bacteria, I'm allergic to this pheromone, because my T cells perceived it as an association of the pneumonia along with the other aldehyde and ether compounds the bacterial infection deposited in my lungs, grass uses this smell to kill bacteria and my bacterial pneumonia likely had this compound bound to it and my t cells associated it with infection and treat its presence as a sign of infection and cause immune distress to impede bacterial infection. If you itch when you sit on grass or find the smell of fresh cut grass and many other plants (watermelon, zucchini) irritating you have some degree of the same allergy. The point of that story is to say that most people don't have such an immune problem and though mine does effect my life it's not crippling, I know this precise problem has killed a number of children with harlequin ichthyosis and is generally more common in people who had chronic skin or respiratory conditions in childhood. The point of all the above is to show how the T-cells are unintelligent and association driven, I was saved by modern antibiotics but my t cells think that it was targeting the aldehyde compounds which cured me because that was successful from their perspective. Back to spike proteins Spike proteins bound to your cells may make the t cells think the whole cell is the foreign body and associate the compounds in ACE2 expression with infection and cause the immune system to attack just about every soft lining in your body, ACE2 expression is present in more than 50% of humans and is present in ventricles which pass fluids that are not necessarily blood and in tissue linings like pleura, key examples being the uterine lining, the placenta, the pericardial sack(pericardium) the testes, kidneys, the vesicles coming from the testes and the kidneys, the entire lymphatic system, the alveoli or bronchial passages in the lungs, there are probably more I'm unaware of, I'd bet they are in isolated systems like the cochlea or the tongue, considering the reports of loss of taste from the virus. Considering other symptoms, skin swelling, the recent discovery of scent receptors in skin, and of expected linkages to the lymphatic system, ACE2 expression may be present in sebaceous glands. The issue with the "vaccines" being predicated upon the spike protein is that the response of our immune systems to this engineered structure is a roll of the dice, it doesn't go inside the cell and do harm, it just bonds to the cell wall at an ACE2 receptor and creates an opening in it or through it by tricking the cell to open for it, the likelihood of the development of an antibody for just the spike protein is pretty low considering it's not doing anything it's not alive and here's the kicker, the spike protein is being made in your cells and is not hooked up to a virus which gets it out of the cells, presumably it gets out of the cells as they die, or maybe they bond to carrier proteins and are carried into blood, it just seems the adenoviral vector vaccines which don't engineer your body but do infect you with an engineered but inert virus with spike protein would be more practical with fewer complications, supposedly sputnikV (adenoviral vector) has fewer blood clot cses proportionally than Jansen and astrazeneca's adenoviral vector "vaccines", the main difference is handling procedures, the american AVV shots are kept at freezing temperatures up to the moment of injection and some countries have stopped doing this and seen clots disappear supposedly, you freeze and thaw any animal cells and the water content causes cells to burst as frezing water expands and becomes sharp at a celular level, probably enough to cause blockages made of exploded cells and vascular tissue to effect a clotting factor or a blockage. the smarter, obviously smarter solution would have been engineering a version of the virus without spike proteins so that it could only have bounced around in blood and pair it with a prophylactic to take after 3 days. Hell if they could have isolated just one virus per inoculation and given people the prophylactic treatment and told to take it every other day 3 days after their shot we would have had a traditional vaccine, no fuss beyond the question of the engineered virus, and broad band immunity, likely enough to function as a wall for a second cycle. People here will tell you we never isolated the virus but here's a chinese paper claiming they did published in nature: https://www.nature.com/articles/s41401-020-0485-4 I'm one to believe this is mostly accurate considering they accurately predicted the effectiveness of protease inhibitors