I would think that it would be messed up more than just in that one area. I don't know though.
Possibly, it could depend on the distance traveled while re-aligning with the layer to continue the print. I have seen some odd behavior with my printer for things like that.
For example, over extrusion due to the head taking too long to move to the other side of the bed while it is still hot enough its basically "auto extruding" then having artifacts afterward because its under-extruding since some material that would have been in the head was dropped on the way.
Depending on how much you are printing you probably should be cleaning the head from time to time too but I would expect more problems if you had a clogged print head.
I thought of that one and put an entirely new print head on for the second print. It's a real head scratcher. Hopefully running that calibration will help.
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