You can pass USB devices to a VirtualBox VM. Get a Win10 VM running and you might be able to run the scanner from that without shutting down and booting into Windows.
Thanks for the tip and I got the scanner recognized and its drivers installed in the 7 VM. CrealityScan also runs under Win7 x64. It was the original plan and why I upgraded to 64 GB of RAM.
Alas, I found that the scanning software needs native access to the machine's 3D acceleration hardware. During scanning it needs to throw the point cloud around among other things.
There doesn't seem to be a good or even any solution for VirtualBox, which I used. I'm done with VMWare for a while after they got on my nerves. Not that I'd expect it to fare much better. I think there was a solution for Nvidia? I use AMD.
I really don't mind booting into the installation on the SSD for the few times I need to. It's a clean and convenient solution for now, which only has that one reboot drawback.
Hopefully the manufacturers will provide native Linux software in the future.